Evaluation of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells.

doi:10.1016/j.toxlet.2014.06.016

Paper

DOI: 10.1016/j.toxlet.2014.06.016

Evaluation of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells.

Published Sep 2, 2014 · Kamonporn Masawang, M. Pedro, H. Cidade

Toxicology letters

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Abstract

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In Vitro Study

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2',4'-dihydroxy-3,4,5-trimethoxychalcone inhibits MCF-7 breast cancer cell growth by causing mitotic catastrophe, potentially offering antitumor activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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