Paper

Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co(III) complexes of 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde thiosemicarbazones.

Published Apr 1, 2012 · E. Ramachandran, Sajesh P. Thomas, P. Poornima

European journal of medicinal chemistry

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Abstract

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In Vitro StudyHighly Cited

Study Snapshot

New cobalt(III) complexes show DNA binding, significant antioxidant activity, and cytotoxic activity against cancer cells, even at low concentrations.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co(III) complexes of 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde thiosemicarbazones.

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