Biological evaluation of indolizine-chalcone hybrids as new anticancer agents.

doi:10.1016/j.ejmech.2017.12.056

Paper

Biological evaluation of indolizine-chalcone hybrids as new anticancer agents.

Published Jan 20, 2018 · Sujin Park, Eun Hye Kim, Jinwoo Kim

European journal of medicinal chemistry

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63

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Abstract

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In Vitro Study

Study Snapshot

Indolizine-chalcone hybrids with 3,5-dimethoxyphenyl group or halogen at meta position show potential as new anticancer agents by inducing caspase-dependent apoptosis of human lymphoma cells.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Biological evaluation of indolizine-chalcone hybrids as new anticancer agents.

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