Experiments on the mode of action of piriprost (U-60,257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophil leukemia cells.

doi:10.1016/0006-2952(87)90111-0

Paper

Experiments on the mode of action of piriprost (U-60,257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophil leukemia cells.

Published May 1, 1987 · M. K. Bach, J. R. Brashler, G. J. White

Biochemical pharmacology

Q1 SJR score

11

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Abstract

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In Vitro Study

Study Snapshot

Piriprost acts as an inhibitor of the 5-lipoxygenase reaction, but its activity in intact cells is likely not due to the inhibition of LTC synthase.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Experiments on the mode of action of piriprost (U-60,257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophil leukemia cells.

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