Paper
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety.
Published Feb 1, 2019 · Maria R Buemi, A. Di Fiore, L. De Luca
European journal of medicinal chemistry
Q2 SJR score
34
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
In Vitro StudyStudy Snapshot
The synthesized compounds 7a, 7b, and 8b show promising inhibition of human carbonic anhydrase II and brain-expressed hCA VII in subnanomolar range, with potential for designing new isoform selective inhibitors.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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