Paper

Facile synthesis of 2-aryl 5-hydroxy benzo[d]oxazoles and their in vitro anti-proliferative effects on various cancer cell lines.

Published Dec 1, 2018 · Neelima D. Tangellamudi, Suchita B Shinde, Venkatesh Pooladanda

Bioorganic & medicinal chemistry letters

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Abstract

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In Vitro Study

Study Snapshot

2-Aryl 5-hydroxy benzo[d]oxazoles show promising anti-cancer properties, with IC 50 values in the range of 0.8-2.8 M, comparable to the known drug doxorubicin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Facile synthesis of 2-aryl 5-hydroxy benzo[d]oxazoles and their in vitro anti-proliferative effects on various cancer cell lines.

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