A facile regioselective synthesis of (5-amino-4-cyano-1H-imidazol-1-yl) benzoic acids

doi:10.1002/JHET.5570440103

Paper

A facile regioselective synthesis of (5-amino-4-cyano-1H-imidazol-1-yl) benzoic acids

Published 2007 · Síria A. Barros, M. S. Gonçalves, A. Oliveira-Campos

Journal of Heterocyclic Chemistry

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Abstract

A simple and efficient method was developped for the synthesis of 3-(5-amino-4-cyano-1H-imidazol-1-yl)-4-substituted benzoic acids 3. These compounds were isolated by intramolecular cyclisation of the corresponding 3-{[(Z)-2-amino-1,2-dicyano-vinyl]amino}methyleneaminobenzoic acids in the presence of base.

Study Snapshot

This method allows for the efficient synthesis of 5-amino-4-cyano-1H-imidazol-1-yl) benzoic acids with regioselective properties, offering potential applications in pharmaceutical and biotechnology industries.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

A facile regioselective synthesis of (5-amino-4-cyano-1H-imidazol-1-yl) benzoic acids

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Citations

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