Paper

Facile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T

Published May 27, 2015 · S. Mal, K. Prathap, Stephen C. Smith

Tetrahedron Letters

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Abstract

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Study Snapshot

Chloramine T trihydrate provides a safe and efficient one-pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines, enabling versatile new synthetic scaffolds without chromatographic purification.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Facile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T

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