Paper

Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B.

Published 2008 · DOI · David M Gooden, Dawn M Z Schmidt, Julie A Pollock

Bioorganic & medicinal chemistry letters

Citations

Influential Citations

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

This study developed a facile synthetic route to substituted trans-2-arylcyclopropylamine inhibitors for human histone demethylase LSD1 and related enzymes, providing access to mechanism-based inhibitors for these enzymes.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B.

References

Citations