Paper
Formation of ionic co-crystals of amphoteric azoles directed by the ionic liquid co-former 1-ethyl-3-methylimidazolium acetate.
Published Jul 27, 2017 · H. Titi, Steven P. Kelley, M. Easton
Chemical communications
Q1 SJR score
7
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Abstract
The ionic liquid (IL) 1-ethyl-3-methylimidazolium acetate was utilized as a liquid-state crystallization agent to form ionic co-crystals using amphoteric azoles selected as model compounds for active pharmaceutical ingredients. Weakly acidic azoles crystallize the IL relatively quickly, while stronger acidic azoles undergo slower ion exchange with the IL to form salts.
Study Snapshot
The ionic liquid 1-ethyl-3-methylimidazolium acetate effectively forms ionic co-crystals of amphoteric azoles, potentially useful for active pharmaceutical ingredients.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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