Paper
Structural and Functional Evidence for Citicoline Binding and Modulation of 20S Proteasome Activity: Novel Insights into its Pro-Proteostatic Effect.
Published Apr 13, 2020 · D. Sbardella, A. Coletta, G. Tundo
Biochemical pharmacology
Q1 SJR score
15
Citations
1
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Citicoline acts as a bimodal allosteric modulator, potentially regulating proteostasis in nervous cells, with potential therapeutic applications in glaucoma, retinal disorders, and neurodegenerative diseases.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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