Functionalisation of 2-Methoxy-6-methylpyridine

doi:10.1080/00397919408011740

Paper

Functionalisation of 2-Methoxy-6-methylpyridine

Published May 1, 1994 · M. A. Gray, L. Konopski, Y. Langlois*

Synthetic Communications

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19

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0

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Abstract

Abstract : Selective bromination of 2-methoxy-6-methylpyridine 2 afforded 5-bromo-2-methoxy-6-methylpyridine 8. Deprotonation of this pyridine derivative in benzylic position or lithium-bromine exchange allowed the regioselective introduction of various electrophiles.

Study Snapshot

Selective bromination of 2-methoxy-6-methylpyridine allows for regioselective introduction of various electrophiles, enabling functionalization of this pyridine derivative.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Functionalisation of 2-Methoxy-6-methylpyridine

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References

Synthesis of milrinone, a cardiotonic agent

Milrinone, a cardiotonic agent, can be synthesized from 6-methyl-5-(4-pyridinyl)-2(1H)-pyridone by a convenient method.

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