Paper

Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.

Published Aug 15, 2009 · Luke R. Odell, M. Nilsson, J. Gising

Bioorganic & medicinal chemistry letters

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Abstract

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In Vitro StudyHighly Cited

Study Snapshot

3-amino-imidazo[1,2-a]pyridines are a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors, with compound 4n being the most potent inhibitor.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.

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