Paper

Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor.

Published May 2, 2005 · S. Courtney, P. Hay, R. Buck

Bioorganic & medicinal chemistry letters

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Abstract

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Study Snapshot

Novel benzoxazol-5-yl acetic acid derivatives show potential as heparanase inhibitors with anti-angiogenic properties and improved DMPK profiles for potential use in vivo models.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor.

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