Giant-cell arteritis with normal erythrocyte sedimentation rate: case report and review of the literature.

Paper

Giant-cell arteritis with normal erythrocyte sedimentation rate: case report and review of the literature.

Published Apr 1, 1993 · S. Zweegman, B. Makkink, C. Stehouwer

The Netherlands journal of medicine

Q3 SJR score

38

Citations

3

Influential Citations

Semantic Scholar

Abstract

A high Erythrocyte Sedimentation Rate (ESR) is often seen as a sine qua non for the diagnosis of giant-cell arteritis. The percentages of histopathologically proven giant-cell arteritis associated with a normal ESR, however, are variously reported as 5 to 30%. We describe a patient with histopathologically proven giant-cell arteritis and a normal ESR. A review of literature identified 34 cases of giant-cell arteritis who showed a normal ESR. Their clinical symptoms and signs are compared with the characteristics of patients with giant cell arteritis and an elevated ESR. No distinctive clinical features were found. A normal ESR cannot be used to exclude the diagnosis of giant-cell arteritis.

Case Report

Study Snapshot

A normal ESR cannot exclude the diagnosis of giant-cell arteritis, as it is common in 5 to 30% of cases.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Giant-cell arteritis with normal erythrocyte sedimentation rate: case report and review of the literature.

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References

Citations

Giant cell arteritis with normal inflammatory markers: case report and review of the literature

Giant cell arteritis with normal inflammatory markers is uncommon but does not rule out the diagnosis, and immediate ultrasound and/or temporal artery biopsy are necessary for accurate diagnosis and treatment.

Giant cell arteritis: ophthalmic manifestations of a systemic disease

Ocular manifestations of giant cell arteritis can vary, and proper diagnosis is crucial for timely intervention and preventing significant morbidity.

Ischemic Optic Neuropathies

Ischemic optic neuropathy is a major cause of blindness or severely impaired vision, with disagreement on its pathogenesis, clinical features, and management.

ICSH review of the measurement of the erythocyte sedimentation rate

The International Council for Standardization in Haematology recommends a standard reference method for measuring erythrocyte sedimentation rate (ESR) using whole blood anticoagulated with EDTA and diluted with sodium citrate or saline (4:1) in Westergren pipettes.

Ischemic Optic Neuropathy

Ischemic optic neuropathies are classified into anterior and posterior types, with anterior ION causing sudden, painless visual loss and posterior ION causing acute vision loss and optic disc atrophy.

Prevalence of a normal C-reactive protein with an elevated erythrocyte sedimentation rate in biopsy-proven giant cell arteritis.

Both elevated ESR and CRP are necessary for diagnosis of giant cell arteritis, as both can be normal in some patients.

Temporal Artery Biopsy: Concise Guidelines for Otolaryngologists

Otolaryngologists must understand the signs, symptoms, and natural history of temporal arteritis to effectively perform temporal artery biopsies and maximize the yield from these procedures.