High-throughput and virtual screening: core lead discovery technologies move towards integration.

doi:10.1016/s1359-6446(00)80056-2

Paper

High-throughput and virtual screening: core lead discovery technologies move towards integration.

Published 2000 · A. Good, S. Krystek, J. Mason

Drug discovery today

Q1 SJR score

35

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0

Influential Citations

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

Virtual screening and high-throughput screening can synergistically enhance lead discovery, but key issues need to be addressed before their potential can be fully realized.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

High-throughput and virtual screening: core lead discovery technologies move towards integration.

References

Citations

Strategies for MALDI-MS method development to investigate different pharmaceutical drug modalities

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Val-CoA, a lead compound, stabilizes SARS-CoV-2 spike trimer receptor-binding domains in the down conformation, potentially attenuating viral transmission and offering a new approach for designing antiviral drugs.

Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer

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