Hydrazine

doi:10.1007/s40278-020-75559-8

Paper

Hydrazine

Published Feb 1, 2020 · F. Roe

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Abstract

A highly reactive base and reducing agent used in many industrial and medical applications. In biological applications, hydrazine and its derivatives exhibit antidepressant properties by inhibiting monoamine oxidase (MAO), an enzyme that catalyzes the deamination and inactivation of certain stimulatory neurotransmitters such as norepinephrine and dopamine. In psychiatry, the use of hydrazine derivatives is limited due to the emergence of the tricyclic antidepressants. (NCI04) Qeios · Definition, February 7, 2020

Study Snapshot

Hydrazine and its derivatives exhibit antidepressant properties by inhibiting monoamine oxidase (MAO), an enzyme that catalyzes the deamination and inactivation of certain stimulatory neurotransmitters such as norepinephrine and dopamine.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Hydrazine

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References

Citations

Acute exposure to hydrazine reported to four United States regional poison centers: reconsidering a paradigm

Occupational exposure to hydrazine during aerospace operations is limited to mucosal and mild pulmonary irritation without significant neurologic, hepatic, or hematologic toxicity.

Colorimetric and ratiometric fluorescent chemodosimeter for the detection of hydrazine via the Ing-Manske reaction in solution as well as in the gaseous state: an experimental and computational investigation

The fluoranthene-phthalimide conjugate (FP) is a highly efficient hydrazine chemodosimeter with high sensitivity and selectivity, enabling quick and easy detection of N2H4 solution and vapour.

Practical Fischer Indolization Using Bench-Stable Arylhydrazine Sulfonate as the Surrogate of Arylhydrazine

Fischer indolization using bench-stable sodium arylhydrazine sulfonate as a surrogate allows for the straightforward synthesis of tetrahydrocarbazoles from anilines, with potential applications in the synthesis of pharmaceutical molecules Rizatriptan and Zol

A first principles study of adsorption of hydrazine on C20, C40 and C60 fullerene nanoclusters

Fullerene C20 has a better sensing ability towards hydrazine than C40 and C60, potentially benefiting cancer research, rocket fuel, and various pharmaceutical products.

Unsupervised Reaction Pathways Search for the Oxidation of Hypergolic Ionic Liquids: 1-Ethyl-3-methylimidazolium Cyanoborohydride (EMIM+/CBH-) as a Case Study.

The mechanism of hypergolic ionic liquid oxidation, using anion-oxidant interactions and computational methods, reveals eight potential products with reactivity barriers of 6-7 kcal/mol.

Selective Electrochemical Reductive Amination of Benzaldehyde at Heterogeneous Metal Surfaces

Electrochemical reductive amination on silver electrocatalysts can efficiently synthesize benzylamine from benzaldehyde and ammonia, offering a promising inner-sphere route for ammonia utilization.

The development of alginate-based amperometric nanoreactors for biochemical profiling of living yeast cells.

Alginate-based amperometric nanoreactors can simultaneously serve as nanofermenters and amperometric detectors for quantifying secondary metabolites in yeast cells, improving our understanding of fermentation processes and yeast biochemistry.