IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. II. IN VIVO MUTAGENESIS BY 5-BROMODEOXYURIDINE AND 2-AMINOPURINE.

doi:10.1016/S0022-2836(64)80213-8

Paper

IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. II. IN VIVO MUTAGENESIS BY 5-BROMODEOXYURIDINE AND 2-AMINOPURINE.

Published Aug 1, 1964 · B. Howard, I. Tessman

Journal of molecular biology

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42

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Abstract

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Study Snapshot

In vivo induction of single-stranded DNA mutations by 5-bromodeoxyuridine and 2-aminopurine reveals that DNA replication involves pairing with a complementary DNA strand, with natural deoxynucleosides acting as competitors for incorporation.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. II. IN VIVO MUTAGENESIS BY 5-BROMODEOXYURIDINE AND 2-AMINOPURINE.

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