Paper

Improved synthesis of 2'-amino-2'-deoxyguanosine and its phosphoramidite.

Published Feb 1, 2006 · Qing Dai, S. Deb, James L. Hougland

Bioorganic & medicinal chemistry

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Abstract

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Study Snapshot

This study developed efficient protocols for obtaining 2'-amino-2'-deoxyguanosine and its phosphoramidite derivatives with fewer steps and higher yields, making them useful for incorporation into oligonucleotides for biochemical applications.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Improved synthesis of 2'-amino-2'-deoxyguanosine and its phosphoramidite.

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