Paper

Induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by a series of 4'-substituted-2,3,4,5-tetrachlorobiphenyls.

Published Dec 30, 1988 · A. Parkinson, P. Thomas, D. Ryan

Toxicology

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Abstract

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Non-RCTAnimal Study

Study Snapshot

Substituted 2,3,4,5-tetrachlorobiphenyls can induce rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase, with the size of the substituent playing a crucial role in enzyme induction.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by a series of 4'-substituted-2,3,4,5-tetrachlorobiphenyls.

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