Paper

Inhibition of D (-)-3-hydroxybutyrate dehydrogenase by malonate analoges.

Published Jan 1, 1975 · A. W. Tan, C. Smith, T. Aogaichi

Archives of biochemistry and biophysics

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Abstract

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In Vitro Study

Study Snapshot

Malonate analogs, particularly methylmalonate, effectively inhibit 3-hydroxybutyrate dehydrogenase activity in various cell types, affecting ketone body formation without affecting intramitochondrial NADH or NADPH levels.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Inhibition of D (-)-3-hydroxybutyrate dehydrogenase by malonate analoges.

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