Paper

Inhibition of mono-oxygenase activities by 1,1,1-trichloropropene 2,3-oxide, an inhibitor of epoxide hydrase, in rat liver microsomes.

Published Jun 1, 1979 · Tsutomu Shimada, Ryo Sato

Biochemical pharmacology

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Abstract

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In Vitro Study

Study Snapshot

1,1,1-trichloropropene 2,3-oxide inhibits mono-oxygenase activities in rat liver microsomes by interacting with cytochrome P-450, which is inducible by phenobarbital administration.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Inhibition of mono-oxygenase activities by 1,1,1-trichloropropene 2,3-oxide, an inhibitor of epoxide hydrase, in rat liver microsomes.

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