Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine.

doi:10.1016/0006-2952(87)90262-0

Paper

Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine.

Published Sep 1, 1987 · Teresa M. Neal, C. Winterbourn, M. Vissers

Biochemical pharmacology

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52

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Abstract

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Study Snapshot

Sulfasalazine's anti-inflammatory properties are primarily due to its azo link, which inhibits neutrophil responses and is closely mimicked by olsalazine, suggesting its potential as an anti-inflammatory agent.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine.

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