Paper

Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium.

Published May 1, 1994 · R. Schwinger, Michael Böhm, A. Koch

The Journal of pharmacology and experimental therapeutics

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Abstract

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In Vitro Study

Study Snapshot

2,3-butanedione monoxime (BDM) is a cardioprotective agent that depresses isometric force development in human myocardium, with a more potent effect in atrial tissue and a shift in calcium sensitivity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium.

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