Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4',5':4,5]thieno(2,3-b)quinolines.

doi:10.1016/j.jphotobiol.2008.09.001

Paper

Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4',5':4,5]thieno(2,3-b)quinolines.

Published Jan 9, 2009 · M. Shahabuddin, M. Gopal, S. Raghavan

Journal of photochemistry and photobiology. B, Biology

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Abstract

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In Vitro Study

Study Snapshot

Chloro-PTQ and morpholino-PTQ show promising antitumor activity against B16F10 melanoma, offering a new intercalation functional group for DNA targeted drug design.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4',5':4,5]thieno(2,3-b)quinolines.

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