Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways

doi:10.1016/j.lfs.2018.03.006

Paper

Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways

Published Apr 15, 2018 · B. Rodenak-Kladniew, A. Castro, P. Stärkel

Life Sciences

Q1 SJR score

68

Citations

3

Influential Citations

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Abstract

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In Vitro Study

Study Snapshot

Linalool induces G0/G1 arrest and apoptosis in HepG2 cells, suggesting it as a promising anticancer agent for HCC therapy.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways

References

Citations