Paper
Marked therapeutic effect of dimyristoylphosphatidylcholine liposomes on carcinoma mice model in vivo.
Published Oct 1, 2000 · R. Ueoka, Y. Matsumoto, A. Kanno
Biological & pharmaceutical bulletin
29
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Abstract
Significantly prolonged survival rate was obtained for the first time using carcinoma mice models after the administration of single-component liposomes of dimyristoylphosphatidylcholine (DMPC) without any drug. An increase in lymphocytes under optical microscope was observed without any increase in the neutrophils count, suggesting that the DMPC liposomes might inhibit the tumor growth as well as increase in lymphocytes in vivo.
Dimyristoylphosphatidylcholine liposomes show potential in prolonging survival rates in carcinoma mice models by inhibiting tumor growth and increasing lymphocytes without causing neutrophils increase.
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