A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

doi:10.1038/nature14412

Paper

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Published Apr 1, 2015 · A. Mbengue, S. Bhattacharjee, T. Pandharkar

Nature

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536

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28

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Abstract

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Study Snapshot

Artemisinins target Plasmodium falciparum's phosphatidylinositol-3-kinase (PfPI3K), a key mediator of artemisinin resistance, making it an important target for malaria elimination.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

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