Paper

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

Published Feb 7, 2020 · E. Schrezenmeier, T. Dörner

Nature Reviews Rheumatology

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Abstract

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Study Snapshot

Hydroxychloroquine and chloroquine effectively treat inflammatory rheumatic diseases by interfering with lysosomal activity and autophagy, altering signaling pathways, and causing retinopathy.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

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