Mechanisms of analgesia by gabapentin and pregabalin – Calcium channel α2-δ [Cavα2-δ] ligands

doi:10.1016/j.pain.2008.11.019

Paper

Mechanisms of analgesia by gabapentin and pregabalin – Calcium channel α2-δ [Cavα2-δ] ligands

Published Mar 1, 2009 · C. Taylor

Pain

Q1 SJR score

190

Citations

5

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Very Rigorous Journal

Highly Cited

Study Snapshot

Gabapentin and pregabalin reduce chronic pain by binding to calcium channel alpha2-delta proteins, not GABAergic, and reducing stimulated transmitter release.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Mechanisms of analgesia by gabapentin and pregabalin – Calcium channel α2-δ [Cavα2-δ] ligands

References

Citations