Paper

Mechanisms underlying the vascular and hypotensive actions of the labdane ent-3-acetoxy-labda-8(17),13-dien-15-oic acid.

Published Mar 5, 2014 · Janaina A. Simplicio, L. Pernomian, M. R. Simão

European journal of pharmacology

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Abstract

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Non-RCTAnimal StudyRigorous Journal

Study Snapshot

Labda-15-oic acid's cardiovascular actions involve activation of the endothelial NO-cGMP pathway, opening of K+ channels, and alteration of calcium mobilization.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Mechanisms underlying the vascular and hypotensive actions of the labdane ent-3-acetoxy-labda-8(17),13-dien-15-oic acid.

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