Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder

doi:10.1038/tp.2016.29

Paper

Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder

Published Mar 1, 2016 · R. Mocking, I. Harmsen, J. Assies

Translational Psychiatry

Q1 SJR score

236

Citations

9

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Meta-Analysis

Very Rigorous Journal

Highly Cited

Study Snapshot

Omega-3 PUFA supplementation shows a beneficial effect on depressive symptoms in major depressive disorder patients, particularly with higher EPA doses and in those taking antidepressants.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder

Sign up to use Study Snapshot

References

Citations

Increased intake of marine fish contributed to a decreased odds of comorbid depressive symptoms and coronary heart disease in Chinese adults

Increased consumption of marine fish is associated with decreased severity of depressive symptoms, potentially benefiting comorbid depressive symptoms and coronary heart diseases in Chinese adults.

Plasma Polyunsaturated Fatty Acid Levels and Mental Health in Middle-Aged and Elderly Adults

Higher plasma levels of omega-3 PUFAs and DHA are associated with lower risks of depressive disorder and anxiety disorder, and may improve mental health in middle-aged and elderly adults.

Omega-3 fatty acid supplementation for depression in children and adolescents.

Omega-3 PUFA supplementation may reduce self-reported depression symptoms in children and adolescents, but the evidence is very uncertain and may not lead to depression remission.

Academician E.M. Kreps – founder оf the science of evolutionary biochemistry of brain lipids

E.M. Kreps is credited with establishing the evolutionary biochemistry of brain lipids, which reveals changes in phospholipid, cerebroside, ganglioside, and fatty acid radical composition during central nervous system evolution.

Unique hunting strategies of the dragonflies and exceptionally high level of eicosapentaenoic acid in brain lipids: Is there a connection?

Dragonflies have a higher level of omega-3 fatty acid in their brains, which may contribute to their unique hunting strategies and cognitive development.

Omega-3 Polyunsaturated Fatty Acids in Depression

Omega-3 fatty acids show potential antidepressant effects, but more research is needed to establish uniform guidelines for their use in treating depressive disorders.

Omega-3 PUFAs’ efficacy in the therapy of coronary artery disease combined with anxiety or depression: a meta-analysis

Omega-3 PUFAs do not alleviate anxiety or depression in coronary artery disease patients.

Management of Depression in Adults: A Review.

Effective first-line depression treatments include specific psychotherapies and more than 20 antidepressant medications, with close monitoring significantly improving treatment success.