Paper

Metabolism of 2,4,5,2',5'-pentachlorobiphenyl in the rat. Qualitative and quantitative aspects.

Published Jul 1, 1976 · P. Chen, J. McKinney, H. Matthews

Drug metabolism and disposition: the biological fate of chemicals

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Abstract

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Non-RCTAnimal Study

Study Snapshot

The major metabolite of 2,4,5,2',5'-pentachlorobiphenyl (5-CB) in male rats is 3'-hydroxy 5-CB, with 89% of radioactivity excreted in the form of metabolites.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Metabolism of 2,4,5,2',5'-pentachlorobiphenyl in the rat. Qualitative and quantitative aspects.

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