Metformin—mode of action and clinical implications for diabetes and cancer

doi:10.1038/nrendo.2013.256

Paper

Metformin—mode of action and clinical implications for diabetes and cancer

Published Mar 1, 2014 · I. Pernicova, M. Korbonits

Nature Reviews Endocrinology

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1,079

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42

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

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Study Snapshot

Metformin lowers glucose levels by inhibiting hepatic gluconeogenesis and may influence tumorigenesis through systemic reduction of insulin levels and energetic stress.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Metformin—mode of action and clinical implications for diabetes and cancer

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