Paper

Methylation of DNA by N-Methyl-N-nitrosourethane and N-Methyl-N-nitroso-N′-nitroguanidine

Published May 1, 1968 · P. D. Lawley

Nature

107

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Abstract

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Study Snapshot

N-Methyl-N-nitrosourethane and N-Methyl-N-nitroso-N′-nitroguanidine can methylate DNA, potentially determining their biological action as mutagens and carcinogens.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Methylation of DNA by N-Methyl-N-nitrosourethane and N-Methyl-N-nitroso-N′-nitroguanidine

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