Paper

Mirtazapine increases glial cell line-derived neurotrophic factor production through lysophosphatidic acid 1 receptor-mediated extracellular signal-regulated kinase signaling in astrocytes.

Published Oct 5, 2019 · K. Hisaoka-Nakashima, Sayaka Taki, Shintaro Watanabe

European journal of pharmacology

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Abstract

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In Vitro StudyRigorous Journal

Study Snapshot

Mirtazapine increases GDNF expression in astrocytes, suggesting a general mechanism underlying the psychotropic effect of antidepressants.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Mirtazapine increases glial cell line-derived neurotrophic factor production through lysophosphatidic acid 1 receptor-mediated extracellular signal-regulated kinase signaling in astrocytes.

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