Model experiments on the molecular mechanism of action of 6-hydroxydopamine.

doi:10.1016/s0026-895x(25)12658-8

Paper

Model experiments on the molecular mechanism of action of 6-hydroxydopamine.

Published Feb 1, 1971 · A. Saner, H. Thoenen

Molecular pharmacology

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179

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2

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

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Study Snapshot

6-hydroxydopamine selectively destroys adrenergic nerve terminals by covalent binding to nucleophilic groups of biological macromolecules, with the high gelectivity of the destructive effect due to efficient uptake into adrenergic nerve terminals.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Model experiments on the molecular mechanism of action of 6-hydroxydopamine.

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