Paper
Green multicomponent synthesis of 1,2-dihydro-pyrimido[1,2-a]-benzimidazole-3-carbonitrile
Published Jul 1, 2008 · Guangmin Liu, Qingqing Shao, S. Tu
Journal of Heterocyclic Chemistry
Q3 SJR score
11
Citations
0
Influential Citations
Abstract
1,2-dihydro-pyrimido[1,2-a]benzimidazole-3-carbonitrile derivatives were synthesized via the three-component reaction of aldehyde, malonodinitrile and 2-aminobenzimidazole in water under microwave irradiation. The new protocol has the advantages of excellent yield, low cost, reduced environment impact, wide scope and convenient procedure.
Study Snapshot
This green, three-component method for synthesizing 1,2-dihydro-pyrimido[1,2-a]-benzimidazole-3-carbonitrile offers excellent yield, low cost, reduced environmental impact, and a wide scope for applications.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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