Nevadensin: Isolation, chemistry and bioactivity

doi:10.22377/IJGP.V4I4.150

Paper

Nevadensin: Isolation, chemistry and bioactivity

Published Oct 1, 2010 · G. Brahmachari

International Journal of Green Pharmacy

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Abstract

Nevadensin (5,7-dihydroxy-6,8,4'-trimethoxyflavone) has already established itself as a promising natural bioactive substance that bears the potential to become a novel “natural lead” in drug discovery programmes. The bioflavonoid exhibited a wide range of significant biological activities including hypotensive, anti-tubercular, antimicrobial, anti-inflammatory, anti-tumour and anti-cancer activities. This review deals with natural sources, isolation, chemistry and biological activities of the flavonoid in detail. The present resume is aimed to boost the ongoing researches on pharmaceutically potential natural “lead molecules” in drug discovery programmes. Key words: Bioactivity, chemistry, isolation, natural sources, nevadensin

Study Snapshot

Nevadensin shows potential as a novel "natural lead" in drug discovery due to its wide range of biological activities, including hypotensive, anti-tubercular, antimicrobial, anti-inflammatory, and anti-tumour effects.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Nevadensin: Isolation, chemistry and bioactivity

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