Pyridines are one of the most important and promising classes of N-heterocycles actively studied in modern organic and medicinal chemistry; in particular, pyridine is a privileged structural motif in drug design. From a synthetic organic chemistry perspective, nitropyridines can be considered as convenient and readily available precursors for a wide range of mono- and polynuclear heterocyclic systems demonstrating diverse activities, such as antitumor, antiviral, anti-neurodegenerative, etc. This review is an analysis of the literature on the use of nitropyridines for the synthesis of biologically active compounds, covering the period from 2015 to the present.

Nitropyridines are convenient and readily available precursors for the synthesis of diverse biologically active compounds, including antitumor, antiviral, and anti-neurodegenerative agents.

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Nitropyridines in the Synthesis of Bioactive Molecules

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