N-Methylformycins. Reactivity with adenosine deaminase, incorporation into intracellular nucleotides of human erythrocytes and L 1210 cells and cytotoxicity to L 1210 cells.

doi:10.1016/0006-2952(79)90463-5

Paper

N-Methylformycins. Reactivity with adenosine deaminase, incorporation into intracellular nucleotides of human erythrocytes and L 1210 cells and cytotoxicity to L 1210 cells.

Published May 1, 1979 · G. Crabtree, R. Agarwal, R. Parks

Biochemical pharmacology

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19

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Abstract

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In Vitro Study

Study Snapshot

N-methyl derivatives of formycin show substrate activity with human erythrocytic adenosine deaminase, can form intracellular nucleotides, and show cytotoxicity to L1210 cells.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

N-Methylformycins. Reactivity with adenosine deaminase, incorporation into intracellular nucleotides of human erythrocytes and L 1210 cells and cytotoxicity to L 1210 cells.

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