Non-alcoholic fatty liver disease (NAFLD): a review of epidemiology, risk factors, diagnosis and management.

doi:10.1111/imj.14709

Paper

Non-alcoholic fatty liver disease (NAFLD): a review of epidemiology, risk factors, diagnosis and management.

Published Nov 24, 2019 · T. Huang, J. Behary, A. Zekry

Internal medicine journal

114

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3

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Abstract

Due to the rising prevalence of obesity and type II diabetes mellitus, non-alcoholic fatty liver disease (NAFLD) is becoming the leading cause of chronic liver disease in the Western world. In some patients, simple steatosis can result in non-alcoholic steatohepatitis (NASH) which over time can lead to liver cirrhosis and its associated sequalae, including hepatocellular carcinoma (HCC). Early identification and management of patients at risk with intensive dietary and lifestyle modification are essential to prevent the development of advanced liver disease and its complications. In this review, we will discuss the epidemiology of NAFLD, pathogenesis, diagnosis, management and surveillance strategies to offset the morbidity and mortality of this disease, as well as liver and non-liver related complications. This article is protected by copyright. All rights reserved.

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Study Snapshot

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease in the Western world, and early identification and management with dietary and lifestyle modifications are essential to prevent complications.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Non-alcoholic fatty liver disease (NAFLD): a review of epidemiology, risk factors, diagnosis and management.

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