Paper

Novel 1,4-diarylpiperidine-4-methylureas as anti-hyperlipidemic agents: dual effectors on acyl-CoA:cholesterol O-acyltransferase and low-density lipoprotein receptor expression.

Published Feb 15, 2009 · Shigehiro Asano, Hitoshi Ban, K. Kino

Bioorganic & medicinal chemistry letters

Citations

Influential Citations

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Novel 1,4-diarylpiperidine-4-methylureas show potential as anti-hyperlipidemic agents by inhibiting ACAT and up-regulating LDL receptor expression, with compound 12f showing superior in vitro effects compared to Avasimibe.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Novel 1,4-diarylpiperidine-4-methylureas as anti-hyperlipidemic agents: dual effectors on acyl-CoA:cholesterol O-acyltransferase and low-density lipoprotein receptor expression.

References

Citations