Paper

Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties.

Published Aug 18, 2017 · M. Cindrić, S. Jambon, Anja Harej

European journal of medicinal chemistry

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Abstract

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In Vitro Study

Study Snapshot

Novel 2-imidazolinyl substituted benzo[b]thieno-2-carboxamides show strong antiproliferative and DNA binding properties, with the strongest selective activity against HeLa cells.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties.

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