Novel imidazo[1,2-a]pyrazine derivatives as potent reversible inhibitors of the gastric H+/K+-ATPase.

doi:10.1016/J.BMC.2007.09.009

Paper

Novel imidazo[1,2-a]pyrazine derivatives as potent reversible inhibitors of the gastric H+/K+-ATPase.

Published 2008 · P. Zimmermann, C. Brehm, W. Buhr

Bioorganic & medicinal chemistry

Q2 SJR score

26

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1

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Abstract

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Study Snapshot

Novel imidazo[1,2-a]pyrazines show potent reversible inhibitory activity against the gastric H+/K+-ATPase, potentially offering potential therapeutic applications for gastric acid pump inhibition.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Novel imidazo[1,2-a]pyrazine derivatives as potent reversible inhibitors of the gastric H+/K+-ATPase.

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