Novel piperazine and morpholine substituted quinolines: Selective synthesis through activation of 3,6,8-tribromoquinoline, characterization and their some metabolic enzymes inhibition potentials

doi:10.1016/j.molstruc.2020.128666

Paper

DOI: 10.1016/j.molstruc.2020.128666

Novel piperazine and morpholine substituted quinolines: Selective synthesis through activation of 3,6,8-tribromoquinoline, characterization and their some metabolic enzymes inhibition potentials

Published Nov 15, 2020 · O. Çakmak, Salih Ökten, Dilek Alimli

Journal of Molecular Structure

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Abstract

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Novel piperazine and morpholine substituted quinolines show potential as drug candidates for treating diseases like glaucoma, epilepsy, Alzheimer's, leukemia, and type-2 diabetes mellitus.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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