The combined use of dimethoxymethane with catalytic amounts of tin(II) bromide and bromomethyl methyl ether cleaves p-methoxybenzyl ethers to give methoxymethyl ethers in good yields. The chemoselective conversion of p-methoxybenzyl ethers in the presence of the benzyl ether function into methoxymethyl ethers has also occurred successfully.

Dimethoxymethane combined with tin(II) bromide and bromomethyl methyl ether effectively converts p-methoxybenzyl ethers into methoxymethyl ethers in good yields and chemoselectively.

Bulletin of the Chemical Society of Japan

A One-Step Conversion of p-Methoxybenzyl Ethers into Methoxymethyl Ethers by the Action of Dimethoxymethane in the Presence of Tin(II) Bromide and Bromomethyl Methyl Ether

Paper

A One-Step Conversion of p-Methoxybenzyl Ethers into Methoxymethyl Ethers by the Action of Dimethoxymethane in the Presence of Tin(II) Bromide and Bromomethyl Methyl Ether

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Citations