Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs.

doi:10.1016/J.BBRC.2004.05.202

Paper

Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs.

Published Jul 23, 2004 · J. Fichna, Jean‐Claude Do‐Régo, J. Costentin

Biochemical and biophysical research communications

Q1 SJR score

34

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0

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Abstract

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In Vitro Study

Study Snapshot

[D-1-Nal3]Morphiceptin is the most potent position 3-substituted morphiceptin analog, with a 26-fold increase in mu-opioid receptor affinity and significant in vivo analgesic activity compared to morphiceptin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs.

References

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