Antibiotic optimization via in vitro glycorandomization

doi:10.1038/NBT909

Paper

Antibiotic optimization via in vitro glycorandomization

Published Nov 9, 2003 · Xun Fu, C. Albermann, Jiqing Jiang

Nature Biotechnology

Q1 SJR score

191

Citations

1

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Highly Cited

Study Snapshot

In vitro glycorandomization (IVG) can effectively diversify glycosylation patterns of complex natural products, potentially leading to new antibiotics with improved targeting, mechanism of action, and pharmacology.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Antibiotic optimization via in vitro glycorandomization

References

Citations