Oxetane cis- and trans β-amino-acid scaffolds from d-xylose by efficient SN2 reactions in oxetane rings: methyl and hydroxymethyl analogues of the antibiotic oxetin, an oxetane β-amino-acid

doi:10.1016/J.TETASY.2004.07.031

Paper

DOI: 10.1016/J.TETASY.2004.07.031

Oxetane cis- and trans β-amino-acid scaffolds from d-xylose by efficient SN2 reactions in oxetane rings: methyl and hydroxymethyl analogues of the antibiotic oxetin, an oxetane β-amino-acid

Published Sep 6, 2004 · S. F. Jenkinson, Tim A. J. Harris, G. Fleet

Tetrahedron-asymmetry

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Abstract

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This study demonstrates efficient synthesis of methyl and hydroxymethyl analogues of the antibiotic oxetin using oxetane cis- and trans -amino-acid scaffolds from d-xylose.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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